tag:blogger.com,1999:blog-5398956932575790.post3811155264283073678..comments2024-01-23T21:37:27.869-08:00Comments on Nick's Myeloma Blog: Asymptotes and secondary cancer...Nickhttp://www.blogger.com/profile/09733312143898687572noreply@blogger.comBlogger9125tag:blogger.com,1999:blog-5398956932575790.post-86697191431798696322011-12-09T03:20:34.044-08:002011-12-09T03:20:34.044-08:00CANCER CARE<a href="http://myhealthcarezone.com/what-is-prostate-cancer.html" rel="nofollow"><br /> CANCER CARE</a>Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5398956932575790.post-84394859671622480972011-01-07T00:22:56.384-08:002011-01-07T00:22:56.384-08:00Interesting development, indeed. I will be continu...Interesting development, indeed. I will be continuing my maintenance treatments and taking the blue and whites nightly. I agree with the previous sentiments that right now, it is worth the potential, but not substantiated, risks. Tine and hindsight may teach us. BTW - I hadn't heard the word asymptote since college - thanks for the jolt back to yesteryear. I write shows and other things for a living - glad to know that some smart guys like you are putting higher field knowledge to work! Best!Sean Murrayhttps://www.blogger.com/profile/06954782169183374420noreply@blogger.comtag:blogger.com,1999:blog-5398956932575790.post-47510661856025532412010-12-16T13:20:14.519-08:002010-12-16T13:20:14.519-08:00Just to let you know Nick I am still continuing to...Just to let you know Nick I am still continuing to read all your posts. I have no comment to make here today, except to agree with all Sandy has written. Keep well and strong.Susie Hemingwayhttps://www.blogger.com/profile/00936508273837230613noreply@blogger.comtag:blogger.com,1999:blog-5398956932575790.post-8714695244073363832010-12-13T19:10:39.395-08:002010-12-13T19:10:39.395-08:00Well, what about the fact that with STC's - wh...Well, what about the fact that with STC's - whether allo or auto - you have a body with either diminished or very fragile immune system which leaves one vulnerable to all kinds of things - secondary cancers included? How do you determine if the secondary situation was CAUSED by a drug instead of a compromised structure? <br /><br />It is so important to do the critical thinking - almost impossible when the doctor finishes telling you the bad news - up front... but taking the time now to have this discussion is truly invaluable. Thank you, Nick.Sandyhttps://www.blogger.com/profile/02265922352726668243noreply@blogger.comtag:blogger.com,1999:blog-5398956932575790.post-67341015177237284982010-12-13T14:56:26.123-08:002010-12-13T14:56:26.123-08:00I recall that the paperwork we signed talked about...I recall that the paperwork we signed talked about other cancers and leukemia in particular. I met TWO MM patients that were over 10 years out from their tandem transplants, both elderly, who were back for a 3rd transplant because they had both contracted leukemia. One woman, one man. Leukemia patients can only have allo, because their cells are too compromised. I thought how ingenious it was that BB collected for more than two and this was clearly one of the reasons. Always weighing the risks with the benefits. A delicate dance and widely held opinions on this or that drug or protocol.Lori Puentehttps://www.blogger.com/profile/11304096696996620733noreply@blogger.comtag:blogger.com,1999:blog-5398956932575790.post-75919845759374818592010-12-13T10:42:53.769-08:002010-12-13T10:42:53.769-08:00Just thinking logically...which is dangerous for a...Just thinking logically...which is dangerous for a numbskull like me....cause and effect between Rev and Acute Myelogenous Leukemia would seem to be hard to validate. Is the Rev causing the cancer, or is there some sort of presidposition? Are patients using other therapies, such as Velcade/Dex or, more significantly, thalidomide (which is a close cousing to Rev) having the same experience?Ed (Blog Adminstrator)https://www.blogger.com/profile/10108073032107709276noreply@blogger.comtag:blogger.com,1999:blog-5398956932575790.post-54311358864470464652010-12-12T20:59:04.706-08:002010-12-12T20:59:04.706-08:00Nick,
I seem to recall that the informed consents ...Nick,<br />I seem to recall that the informed consents I signed before each of my 3 transplants warned of a small risk of leukemia from the chemo used in the transplant (usually melphalan). In my view the risk of AML or other blood cancers is extremely small when compared to the risks attendant with prematurely discontinuing a revlimid based maintenance regime. Haven't all of us who've gone through high dose chemo had to do this risk benefit analysis? Seems to be a no brainer to me given the mortality rate associated with untreated myeloma.dan pattersonhttps://www.blogger.com/profile/01422820512237999017noreply@blogger.comtag:blogger.com,1999:blog-5398956932575790.post-28937799444233440292010-12-12T14:35:25.091-08:002010-12-12T14:35:25.091-08:00I am with you on the Rev. Let me know what you hea...I am with you on the Rev. Let me know what you hear from BB! I have put in the same question to Dr. J and will be in his office in a week. Also, would you mind emailing me your current maintenance regiment? We are putting our game plan together for 2011 and I want to compare notes. <br /><br />Keep dominating Nick!<br />PhilAnonymoushttps://www.blogger.com/profile/04782359902659250198noreply@blogger.comtag:blogger.com,1999:blog-5398956932575790.post-68199246147662057502010-12-12T08:19:55.605-08:002010-12-12T08:19:55.605-08:00Nick, thanks for the post. I am still concerned a...Nick, thanks for the post. I am still concerned about my little pill as well. I am on my 20th maintenance cycle. Please let us know as you find out from BB, and I hope other users of REV will comment.<br /><br />Until the newer drugs came on the scene, it was a much more difficult decision. Perhaps now the decision to discontinue may (I repeat may) be easier know that something will be in place in case I need it. The newer meds didn't work for me when I started, but DPASE + ASCT + REVMaint seem to be working so far.<br /><br />Very tough decision :-(Hanna Ostrowieckihttps://www.blogger.com/profile/08187481890900457483noreply@blogger.com